BIOPRINTING MULTI-CELLULAR LIVER MODELS

  • The liver plays a central role for drug metabolism and toxicity. Understanding liver function is very important for pharmacology and toxicologyhttps://www.axt.com.au/wp-content/uploads/Fluicell-Biopixlar-liver-model-application-AXT.pdf research, especially in the context of drug-induced liver toxicity, the leading cause of acute liver failure, and for increased knowledge of liver diseases.

    Cell-based tissue models are important important components in the path towards increased understanding of tissue and organ function. To achieve biological relevance, cell-based tissue models need to mimic the cellular architecture found in organs

    With Biopixlar, it is possible to create complex multi-cellular tissue models in 3D with single-cell precision. Here, we show how the unique single-cell printing technology of Biopixlar can be used to create detailed, multicellular liver models that improve hepatocyte functionality.

    To read this application note click here